PARIS — As part of its quest for longevity, LVMH Moët Hennessy Louis Vuitton’s research-and-development division and Integrated Biosciences have formed a research partnership to discover new chemical entities targeting molecular-level aging.
Their partnership is multiyear and meant to leverage Integrated Biosciences’ synthetic biology and artificial intelligence-based platform for science-backed youth and beauty products. Financial terms of the collaboration were not disclosed.
Beauty companies are increasingly focused on longevity, which is about health span — in other words, finding ways for people to experience more healthful and beautiful lives for a longer period.
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Redwood Shores, Calif.-based Integrated Biosciences is able to train deep learning models to screen virtually hundreds of thousands of molecules to identify chemical compounds that strongly modulate age-related biological phenotypes, the company said in a statement.
It is eligible to receive payments based on achievement of some near-term discovery, development and commercial milestones.
Integrated Biosciences, which was founded by scientist at MIT, Harvard University and the University of California Santa Barbara, recently closed a $17.2 million seed funding round led by Sutter Hill Ventures. Using AI, Integrated Biosciences discovered new senolytic compounds, which are antiaging chemical entities that selectively clear pathological senescent “zombie” cells.
“Our partnership with Integrated Biosciences perfectly embodies our vision: to expand the frontiers of scientific discovery, fueling transformative innovations in beauty,” said Bruno Bavouzet, president of LVMH Recherche, in the statement. “This represents a unique opportunity to evaluate thousands of potential bioactives concurrently, revolutionizing the pace of our research for the benefit of all our brands, amongst them our flagship — Maison Parfums Christian Dior. By combining our skin research expertise with their AI and aging research, we are taking a decisive step in understanding and molecularly addressing age-related cellular pathways.”
“This collaboration with LVMH Recherche, a global leader in luxury consumer product R&D, represents a significant step forward in our shared commitment to combating aging through cutting-edge science,” said Felix Wong, cofounder and chief executive officer of Integrated Biosciences. “We are excited to integrate our proprietary technology platform with LVMH Recherche’s scientific programs, leveraging our ability to control biological stress responses to develop novel, targeted bioactive molecules. Our combined efforts have the potential to unlock biologically functional products that could transform how people age.”
Advances are being made on which biomarkers to home in on to identify biological age, which is not timed with a clock. At Dior, which has created a scientific advisory board on reverse-aging, they’re testing the impact of some formula extracts on different biomarkers with the targets of senescence and “inflammaging.” The latter is a low-grade inflammation that develops with age.The research on longevity is structuring Dior’s science. Some of the brand’s products already have longevity claims, such as Dior Prestige La Crème. Its La Micro-Huile de Rose gives micro-nutrition to skin, while Le Nectar Premier impacts senescence. Used together, they can have a synergistic effect, according to Dior.
